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Therapeutic Index

PARAFEN

Each 5 ml contains:

Composition:
Paracetamol IP........................................................62.5 mg
IbuprofenIP................................................................100 mg
Flavoured Syrup Base....................................................q.s.

Indications :
Combinations of Ibuprofen & Paracetamol are available as they supplement each other`s action. Non-articular rheumatic conditions, rheumatoid or osteoarthritis. Cervical spondylosis, infective inflammation & dental conditions. Pain, fever associated with inflammation.

Description:
Ibuprofen is an NSAID which is believed to work through inhibition of cyclooxygenase (COX), thus inhibiting prostaglandin synthesis. There are at least 2 variants of cyclooxygenase (COX-1 and COX-2). Ibuprofen inhibits both COX-1 and COX-2. It appears that its analgesic, antipyretic, and anti-inflammatory activity are achieved principally through COX-2 inhibition; whereas COX-1 inhibition is responsible for its unwanted effects on platelet aggregation and the GI mucosa.

Contraindications
Ibuprofen tablets or ibuprofen children's suspension should not be used in patients who have previously exhibited hypersensitivity to the drug, or in individuals with the syndrome of nasal polyps, angioedema, and bronchospastic reactivity to aspirin or other nonsteroidal anti-inflammatory agents. Anaphylactoid reactions have occurred in such patients.

Dosage: As per the physician’s advice.

Presentations:     60 ml                   
                                 MRP         Retailer       Stockiest
                                12.00          9.60                8.64 

       
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