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Therapeutic Index

FANTIZOLETM

Each uncoated tablet contains :
Composition:
Fluconazole I.P. .............................................................150 mg
Excipients ...............................................................................q.s.

Indications:  
Fantizole is used to treat fungal infections, including yeast infections of the vagina, mouth, throat, oesophagus (tube leading from the mouth to the stomach), abdomen (area between the chest and waist), lungs, blood, and other organs. Fantizole is also used to treat meningitis (infection of the membranes covering the brain and spine ) caused by fungus.

Description:
As with all azole antifungal agents, fluconazole works principally by inhibition of cytochrome P450 14a-demethylase (P45014DM). This enzyme is in the sterol biosynthesis pathway that leads from lanosterol to ergosterol. Fluconazole inhibits ergosterol synthesis in the cell wall of yeast and other fungi.
In Candida albicans, fluconazole may also inhibit the transformation of blastospores into the invasive mycelial form. Fluconazole is absorbed quickly after oral administration and is widely distributed

Side-Effects
Fluconazole is generally quite well tolerated. In common with all azole antifungal agents, fluconazole may cause hepatotoxicity.

Dosage: As per the physician’s advice.

Presentations:        
                                            
MRP            Retailer        Stockist
                 
1 tablet            31.10             24.88              22.39
                 
4 tablets       122.40             97.92              88.12
 
       
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