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Each
hard gelatin capsule contains:
Composition:
Amoxycillin Trihydrate I.P........................................
........250 mg
(equivalent to Amoxycillin) Cloxacillin Sodium I.P...........250
mg
(Equivalent to cloxacillin) Lactic Acid Bacillus. 80
millino Spores
Indications:
Lower
respirator tract, skin and soft tissue,urinary tract and
post-operative infections. Osteomyelitis, gynaecological,
serious infections like septicaemia, bacterial
endocarditis, brain abscess and bacterial meningitis.
Description:
Amoxicillin binds to penicillin-binding protein 1A
(PBP-1A) located inside the bacterial cell well.
Penicillins acylate the penicillin-sensitive
transpeptidase C-terminal domain by opening the lactam
ring. This inactivation of the enzyme prevents the
formation of a cross-link of two linear peptidoglycan
strands, inhibiting the third and last stage of
bacterial cell wall synthesis. Cell lysis is then
mediated by bacterial cell wall autolytic enzymes such
as autolysins; it is possible that amoxicllin interferes
with an autolysin inhibitor.
Contraindication
A history of allergic reaction to any of the
penicillins is a contraindication.
Dosage
: Adults : 500 mg-1g of combination thrice daily. Children :
50-100mg/kg body -wt. daily in 3 divided doses.
Presentations: 10 tablets
MRP Retailer
Stockiest
38.00 30.40
27.36
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