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Compositions:
Aqua/Water,
Cetearyl , Alcohol, Deceth, Propylene Glycol, Laureth,
Oleth-30, Ammonium Hydroxide,
Lauric Acid,
Hexadimethrine Chloride, Glycol Distarate, Resorcinol,
ethanol.
Indications:
Controls
hair fall.
Descriptions:
The present work was undertaken to study in hairdressers
exposed to several irritants and allergens (prevalently
hair-dyeing) and affected by hand contact dermatitis the
possible correlation between exposure and
direct-oxidative DNA damage, production of tumour
necrosis factor alpha (TNFα) and allergic inflammatory
disease. We evaluated in 19 hairdressers with hand
contact dermatitis, 14 allergic contact dermatitis (ACD)
and 5 irritant contact dermatitis (ICD) and in a
selected control group TNFα serum levels by ELISA and
direct-oxidative DNA damage by Fpg (formamido-pyrimidine-glycosylase)-modified
Comet test on blood. Hairdressers were divided on the
basis of number of hair-dyeing carried out weekly into 2
groups: low-exposure (<60 hair-dyeing/week) and
high-exposure hairdressers (≥60 hair-dyeing/week) that
reflect also the exposure to other allergens and
irritants and 2 different tasks (hairdressers and
apprentice hairdressers, respectively).
Serum levels of TNFα in hairdressers with ACD were
significantly higher than controls with a correlation to
exposure level. Significant DNA damage in ICD
hairdressers with higher exposure as compared to
controls was found. These findings suggest that
occupational exposure can induce in hairdressers,
particularly ICD, DNA damage, increase the TNFa levels
particularly in ACD and induce allergic sensitization,
suggesting a relationship between direct-oxidative DNA
damage, TNFα production and allergic inflammatory
disease.
Presentations:
MRP Retailer
Stockist
5 ml 5.00
4.00
3.60
100 ml 98.00
78.40
70.56 |
